Date & Time of Session - 4/21/26 - from 12:00 - 1:00PM

Overview
Myasthenia gravis is a complex autoimmune disorder characterized by autoantibodies that disrupt neuromuscular transmission, leading to fluctuating muscle weakness and potentially life-threatening respiratory failure known as myasthenic crisis. Managing these acute exacerbations requires care teams to quickly identify triggers, provide specialized supportive care, and navigate the nuances of therapies like IVIG and PLEX.

The treatment landscape for refractory myasthenia gravis has undergone a shift with the rapid emergence and FDA approval of novel biologic therapies. This grand round is designed to bridge the gap between traditional management and these emerging therapies, emphasizing the pharmacist's critical role in both acute crisis management as well as optimizing dosing, ensuring medication safety, and coordinating the complex transition of care for patients with refractory disease.

Objectives
Upon completion of this activity, participants will be able to:
1. Discuss the pathophysiology of myasthenia gravis and its effect on neuromuscular transmission
2. Review strategies for myasthenia gravis crisis management
3. Evaluate biologic therapies used in refractory myasthenia gravis by comparison of mechanism of action, landmark trials, and clinical pearls

    Target Audience
    Pharmacists, residents, and students

    Special Services
    If you require special assistance to attend this event, please call Megan Russell at (304) 550-0896.

    Speaker:
    Kennedy Brennan, PharmD
    PGY1 Acute Care Pharmacy Resident
    University of Kentucky College of Pharmacy
    Lexington, Kentucky

    Session date: 
    04/21/2026 - 12:00pm EDT to 06/19/2026 - 11:59pm EDT
    Add to calendar: 
    • 1.00 ACPE

      In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

      This knowledge-based activity will award 1.00 contact hour(s) (0.100 CEUs) of continuing pharmacy education credit in states that recognize ACPE providers. Course JA-UAN Number: JA0000312-0000-25-046-L01-P

    • 1.00 Participation
      UK Healthcare CECentral certifies this activity for 1.00 hour(s) of participation.
    Please login or register to take this course.
    Faculty List: 
    Speaker(s)

    Kennedy Brennan, PharmD

    has no relevant financial relationships to disclose at this time.