Date & Time of Session - 1/7/26 - from 2:30 - 3:30PM

Overview
For patients undergoing CRRT, anticoagulation is an essential aspect of care in order to maintain circuit patency and function. Traditional options for anticoagulation consist of heparin and citrate. However, these therapies present challenges in patients with elevated bleeding risk or organ dysfunction. Epoprostenol, a prostacyclin analog, has emerged as a potential alternative anticoagulant for patients undergoing CRRT. This presentation will review current recommendations, explore the role and mechanism of epoprostenol, and compare available strategies for anticoagulation in patients undergoing CRRT. 

SGLT2 inhibitors are emerging as a therapeutic option for pediatric CKD, a field where current treatments are extrapolated from adult data. Recent pediatric case series and small clinical trials have supported the use of SGLT2 inhibitors for pediatric CKD. Importantly, the results of the ongoing DOUBLE PRO-TECT Alport trial are highly anticipated, as they represent a significant step in assessing the role of SGLT2 inhibitors in pediatric kidney protection. This presentation will provide the most up to date information on clinical evidence for use of SGLT2i in pediatric CKD.

 

Objectives
Upon completion of this activity, the participant will be able to:
1. Describe current recommendations regarding anticoagulation for patients undergoing CRRT
2. Recognize how epoprostenol would work as an anticoagulant in CRRT
3. Compare/contrast current options for anticoagulation in CRRT
4. Describe the mechanism of action, safety profile, and potential adverse effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors in pediatric Chronic Kidney Disease (CKD). 
5. Evaluate current evidence for the use of SGLT2 inhibitors in pediatric CKD. 
6. Formulate evidence-based recommendations for the integration of SGLT2 inhibitors into pediatric COD management.

Target Audience
Pharmacists, physicians, nurses, fellows and residents

Speaker
Elleigh Shepherd, PharmD
PGY1 Pharmacy Resident 
Norton Children’s Hospital
Louisville, Kentucky

Session date: 
01/07/2026 - 3:00pm EST to 03/07/2026 - 11:59pm EST
Add to calendar: 
  • 1.00 ACPE

    In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

    This knowledge-based activity will award 1.00 contact hour(s) (0.100 CEUs) of continuing pharmacy education credit in states that recognize ACPE providers.

  • 1.00 AMA PRA Category 1 Credit™

    In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

    This Live activity is designated for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

  • 1.00 ANCC (UK Healthcare CECentral)

    In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

    The maximum number of hours awarded for this Continuing Nursing Education activity is 1.00 nursing contact hour(s).

  • 1.00 IPCE

    In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

    This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit(s) for learning and change.

  • 1.00 Participation
    UK Healthcare CECentral certifies this activity for 1.00 hour(s) of participation.
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Faculty List: 
Speaker(s)

Charles Iles

has no relevant financial relationships to disclose at this time.

Elleigh Shepherd, PharmD

has no relevant financial relationships to disclose at this time.