Dr. Yan is a radiation oncology faculty member at the University of Kentucky with over 17 years of clinical and research experience. A physician-scientist and entrepreneur at the interface of advanced radiation therapy, translational immunology, and medical device innovation, he is internationally recognized for his contributions to stereotactic ablative radiation techniques, radiation-induced lymphopenia research, and computational immune modeling. His work bridges the gap between cutting-edge oncology practice and next-generation software-driven clinical tools, with a vision anchored in precision medicine and immune-guided cancer therapy.

Dr. Yan's clinical practice spans a broad spectrum of technically advanced radiation modalities, with particular focus on:

• Stereotactic Central/Core Ablative Radiation Therapy (SCART) — Phase I completed and published in Frontiers in Oncology
• Stereotactic Body Radiation Therapy (SBRT) for thoracic, hepatic, and extracranial targets
• Stereotactic Radiosurgery (SRS) for brain tumors including glioblastoma (GBM)
• Head & neck radiation with immune-directed sequencing (HN-IDIS framework)
• CyberKnife and advanced image-guided radiation delivery platforms