Date & Time of Session - 10/12/26 - from 12:00 - 1:00 PM

Overview
T-cell–engaging bispecific antibodies represent a newer and rapidly expanding area of cancer therapy, with several agents currently on formulary at St. Elizabeth Healthcare. While step-up dosing and the associated monitoring are primarily conducted at the Edgewood campus, patients receiving ongoing therapy may receive care or present for evaluation at other locations throughout the health system. These therapies are associated with unique and potentially serious toxicities, particularly cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). Because pharmacists outside of oncology may not routinely encounter these agents, familiarity with their adverse effects and management may be limited. This topic was therefore selected to increase pharmacist awareness of T-cell–engaging bispecific antibodies, improve recognition of CRS and ICANS, and familiarize pharmacists with institutional protocols and resources available for the timely management of these toxicities..

Objectives
Upon completion of this activity, participants will be able to:
1. Explain T-cell–engaging bispecific antibodies, their mechanism of action, and their evolving role in cancer treatment.
2. Identify signs and symptoms of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS)
3. Distinguish their severity based on established grading criteria.
4. Discuss the pharmacologic management of CRS and ICANS associated with T-cell–engaging bispecific antibodies.
5. Locate relevant St. Elizabeth Healthcare protocols and resources for the management of patients receiving T-cell–engaging bispecific antibodies.

 

Target Audience
Free 1 credit hour of Continuing Education for St Elizabeth Health Care providers, Pharmacists, Residents and Students

Special Services
If you require special assistance to attend this event, please call Deanna Fliehman at (859) 301-6191

Speaker
Samira Samarbakhsh, PharmD
PGY2 Oncology Pharmacy Resident
St Elizabeth Healthcare - Edgewood, Kentucky

Session date: 
10/12/2026 - 12:00pm EDT to 12/10/2026 - 11:59pm EST
Location: 
St. Elizabeth Healthcare
1 Medical Village Drive
Edgewood, KY 41017
United States
See map: Google Maps
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  • 1.00 ACPE

    In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.

    This knowledge-based activity will award 1.00 contact hour(s) (0.100 CEUs) of continuing pharmacy education credit in states that recognize ACPE providers. Course JA-UAN Number: JA0000312-9999-26-007-L01-P

  • 1.00 Participation
    UK Healthcare CECentral certifies this activity for 1.00 hour(s) of participation.
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Faculty List: 
Speaker(s)

Samira Samarbakhsh, PharmD, MHS

has no relevant financial relationships to disclose at this time.