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ForwardPediatric Bone Day
Join us for an educational day of learning about common genetic bone diseases in children and how best to diagnose and treat them.
Attendance is In-person or zoom. Registration Required.
In-person attendance is located at the University of Kentucky in the Healthy Kentucky Research Building, room 150. Lunch will be provided. For zoom attendees, a link will be sent after you complete registration.
Topics and Speakers
Overview of Pediatric Inherited Bone Disease
-Dr. Evangelia Kalaitzoglou, UK Children's Hospital
Operating on Children with Bone Health Differences
-Dr. Vishwas Talwalkar, Shriner's Hospital for Children
Genetic testing in pediatric patients with Inherited Bone Disease
-Dr. Yuri Zarate, UK Children's Hospital
Beyond Rickets: Modern Management of X-linked Hypophosphatemia Across the Lifespan
-Dr. Halley Wasserman, Cincinnati Children's Hospital
Hypophosphatasia: Clinical Consequences of Low ALP
- Dr. Joshua Yang, Orlando Health Arnold Palmer Hospital for Children
Target Audience
Physicians, Nurses, APPs, researchers
Learning Objectives
Upon completion of this activity, participants will be able to:
- Differentiate the key clinical and biochemical features of X-linked hypophosphatemia (XLH) from other causes of rickets and osteomalacia.
- Outline the systematic steps in evaluating pediatric patients with suspected bone disorders, including history, physical examination, imaging, and laboratory investigations.
- Compare conventional and biologic treatment options for XLH, integrating patient age, disease severity, and multidisciplinary management goals.
- Explain the genetics and inheritance patterns of hypophosphatasia (HPP) and recognize low alkaline phosphatase as a diagnostic biomarker.
- Formulate a long-term multidisciplinary care plan for patients with XLH transitioning from childhood to adulthood.
Pediatric Bone Day
Friday, October 17
Venue: HKYB 150 & Zoom
Agenda
10:00 – 10:30 AM
Registration / Sign-In
Facilitators: Emily & Amber
10:30 – 10:45 AM
Opening Remarks & Introduction of First Speaker
Dr. Rao
10:45 – 11:30 AM
Speaker 1: Evangelia Kalaitzoglou, MD — UK Children’s Hospital
Topic: Overview of Pediatric Inherited Bone Disease
Describe clinical features of the most common pediatric bone disorders
Outline the steps in clinical evaluation of patients with pediatric bone disorders
11:30 AM – 12:15 PM
Speaker 2: Vishwas R. Talwalkar, MD — Shriners Hospital for Children
Topic: Operating on Children with Bone Health Differences
Identify the types of operations common among children with inherited bone disease
Discuss strategies to synergize medical and surgical treatment
12:15 – 1:15 PM
Lunch & Networking
(Boxed lunch provided)
1:15 – 2:00 PM
Speaker 3: Yuri A. Zarate, MD, MBA — UK Children’s Hospital
Topic: Genetic Testing in Pediatric Patients with Inherited Bone Disease
Compare the different types of clinically available genomic diagnostic tests
Describe genetic counseling issues that arise when utilizing genomic testing
2:00 – 2:45 PM
Speaker 4: Halley M. Wasserman, MD — Cincinnati Children’s Hospital
Topic: Beyond Rickets: Modern Management of X-linked Hypophosphatemia (XLH) Across the Lifespan
Identify clinical and biochemical features that distinguish XLH from other causes of rickets and osteomalacia
Compare conventional and biologic treatment options for XLH
Outline long-term, multidisciplinary care needs as patients transition from childhood to adulthood
2:45 – 3:00 PM
Afternoon Break
(Coffee & cookies provided)
3:00 – 3:45 PM
Speaker 5: Joshua Yang, MD — Orlando Health Arnold Palmer Hospital for Children
Topic: Hypophosphatasia: Clinical Consequences of Low ALP
Discuss the genetics and inheritance patterns of HPP
Recognize low ALP as a key biomarker for HPP
3:45 – 4:30 PM
Panel Discussion & Q&A
All Speakers
4:30 – 4:45 PM
Closing Remarks & Acknowledgments
Dr. Rao
Planners
Emily Thomas ([email protected]) has no relevant financial relationships to disclose at this time.
Amber Williams ([email protected]) has no relevant financial relationships to disclose at this time.
Speakers
Evangelia Kalaitzoglou, MD has no relevant financial relationships to disclose at this time.
Vishwas R. Talwalkar, MD currently has a financial relationship with Wolters Kluwer
Yuri A. Zarate, MD, MBA currently has a financial relationship with Biomarin
Halley M. Wasserman, MD currently has a financial relationship with Kyowa Kirin, Ultragenyx and Calcilytix
Joshua Yang, MD currently has a financial relationship with Kyowa Kirin, Alexion, Tolmar, Sanofi, Abbvie, Azunity, Ascendis, Novo Nordisk
In support of improving patient care, University of Kentucky HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
CME
This live activity is designated for a maximum of 4.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
Other
UK Healthcare CECentral certifies this activity for 4.5 hours of participation.
Available Credit
- 4.50 AMA PRA Category 1 Credit™
In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.
This Live activity is designated for a maximum of 4.50 AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.
- 4.50 ANCC (UK Healthcare CECentral)
In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.
The maximum number of hours awarded for this Continuing Nursing Education activity is 4.50 nursing contact hour(s).
- 4.50 IPCE
In support of improving patient care, UK HealthCare CECentral is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), the American Nurses Credentialing Center (ANCC), and the Association of Social Work Boards (ASWB) to provide continuing education for the healthcare team.
This activity was planned by and for the healthcare team, and learners will receive 4.50 Interprofessional Continuing Education (IPCE) credit(s) for learning and change.
- 4.50 ParticipationUK Healthcare CECentral certifies this activity for 4.50 hour(s) of participation.