Date & Time of Session - 2/9/26 - from 12:00 - 1:00 PM

Overview
Tyrosine Kinase Inhibitors (TKIs) have revolutionized the oncology landscape, shifting the treatment paradigm toward targeted oral therapies for malignancies such as Chronic Myeloid Leukemia (CML), Non-Small Cell Lung Cancer (NSCLC), and HER2-positive breast cancer. While TKIs offer patients the convenience of at-home administration compared to traditional intravenous chemotherapy, they introduce unique clinical challenges, including complex dosing schedules, significant drug-food interactions, and distinct toxicity profiles.

As oncology patients frequently transition between care settings, the risk for medication errors and therapy gaps increases. It is vital for both inpatient and outpatient pharmacists to synchronize their management strategies—from verifying admission orders and screening for acute drug interactions to coordinating with specialty pharmacies for discharge. This presentation aims to equip pharmacists with the clinical and operational expertise necessary to ensure seamless TKI continuity and optimize patient outcomes throughout the transitions of care.

Objectives
Upon completion of this activity, participants will be able to:
1. Define Tyrosine Kinase Inhibitor (TKI) therapy and its role in the management of solid and hematologic malignancies.
2. Review common oral TKI agents and the rationale for their use based on specific molecular targets and mutations.
3. Discuss key pharmacy considerations for oral TKI management, including drug-interaction screening, absorption requirements, and specialty pharmacy coordination.
4. Assess common TKI-associated toxicities and the pharmacist's role in developing monitoring plans and providing patient education for transitions of care.

Target Audience
Free 1 credit hour of Continuing Education for St Elizabeth Health Care providers, Pharmacists, Residents and Students

Special Services
If you require special assistance to attend this event, please call Deanna Fliehman at (859) 301-6191

Speaker
Winter Stadtlander, PharmD
PGY2 Oncology Pharmacy Resident
St Elizabeth Healthcare - Edgewood, Kentucky